Distribution of inositol 1,4,5-trisphosphate receptor mRNA in mouse tissues
نویسندگان
چکیده
منابع مشابه
Structure-function relationships of the mouse inositol 1,4,5-trisphosphate receptor.
The homotetrameric complex of inositol 1,4,5-triphosphate (InsP3) receptors displays a Ca2+ release activity in response to InsP3 molecules. Structure-function relationships of the mouse cerebellar InsP3 receptor have been studied by analyses of a series of internal deletion or C-terminal truncation mutant proteins expressed in NG108-15 cells. Within the large cytoplasmic portion of the InsP3 r...
متن کاملThe Inositol 1,4,5-Trisphosphate Receptor of Cerebellum
A B S T RA C X The inositol 1,4,5-trisphosphate receptor (InsPaR), an intracellular calcium release channel, is found in virtually all cells and is abundant in the cerebellum. We used Mn 2+ as a tool to study two aspects of the cerebellar InsP3R. First, to investigate the structure of the ion pore, Mn 2+ permeation through the channel was determined. We found that Mn 2+ can pass through the Ins...
متن کاملThe Inositol 1,4,5-Trisphosphate Receptor of Cerebellum
A B S T RA C X The inositol 1,4,5-trisphosphate receptor (InsPaR), an intracellular calcium release channel, is found in virtually all cells and is abundant in the cerebellum. We used Mn 2+ as a tool to study two aspects of the cerebellar InsP3R. First, to investigate the structure of the ion pore, Mn 2+ permeation through the channel was determined. We found that Mn 2+ can pass through the Ins...
متن کاملThe Inositol 1,4,5-Trisphosphate Receptor of Cerebellum
A B S T RA C X The inositol 1,4,5-trisphosphate receptor (InsPaR), an intracellular calcium release channel, is found in virtually all cells and is abundant in the cerebellum. We used Mn 2+ as a tool to study two aspects of the cerebellar InsP3R. First, to investigate the structure of the ion pore, Mn 2+ permeation through the channel was determined. We found that Mn 2+ can pass through the Ins...
متن کاملInositol trisphosphate receptor Ca2+ release channels.
The inositol 1,4,5-trisphosphate (InsP3) receptors (InsP3Rs) are a family of Ca2+ release channels localized predominately in the endoplasmic reticulum of all cell types. They function to release Ca2+ into the cytoplasm in response to InsP3 produced by diverse stimuli, generating complex local and global Ca2+ signals that regulate numerous cell physiological processes ranging from gene transcri...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1990
ISSN: 0014-5793
DOI: 10.1016/0014-5793(90)80294-s